From the other side of the consultation, briefly. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.
If somebody has the primary source to hand I would rather cite it than paraphrase it.
Following on from tony_orlando — and this may be the naive question:
Which effects tachyphylax and which persist, because the answer explains why tolerability improves while the appetite effect keeps working?
Dr.Martinez said:Start from the measurement rather than the conclusion.
I read this differently from Dr.Martinez, on substance rather than tone. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.
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View ResultsDr.Martinez said:Start from the measurement rather than the conclusion.
Right, and the exception is worth naming rather than left implied, because the exception is where people get into trouble.
Worth separating that from the pharmacology, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.
Moderator note: the sourcing question belongs in the vendor section and has been split out. Tagging this one for the weekly digest.