lisa_labSD said:Steady state is faster than people expect: half-life about five days, so you are at plateau in roughly three to four weeks rather than five.
Genuinely useful, thank you. I had the facts and not the framework. Adding it to my notes with a link back to this thread.
Clinical perspective, offered as context rather than as advice.
Sleep changes on sleep apnoea: anyone else sleeping differently? I've been sleeping lighter since starting week 5.
My theory: the weight loss has improved my sleep apnea (confirmed by recent sleep study — AHI dropped from 23 to 4). Better oxygenation at night = better sleep quality = more energy during the day. It's a virtuous cycle.
Dr.BariatricHTX said:SURMOUNT-1 landed around 20.9% mean weight loss at 15mg over 72 weeks, against roughly 15% for semaglutide 2.4mg in STEP 1.
Month 16 update on sleep apnoea: down 28 lbs from my starting weight of 253 lbs. Here's what's changed beyond the scale:
- No longer pre-diabetic (A1C normalized)
- Off blood pressure medication
- Can tie my shoes without getting winded
- Sleep apnea resolved — returned my CPAP
- Confidence level: through the roof
This medication has genuinely given me my life back. I'm not exaggerating. 🙌
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View ResultsThe figures, for anyone assembling their own picture. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.