PharmD_Rodriguez said:Mood changes on mental health: I want to be transparent — I went through a rough patch emotionally around month 2.
I read this differently from PharmD_Rodriguez, on substance rather than tone. I would be careful about how confidently the flatness reports get attributed. Rapid weight loss, a large deficit and disrupted sleep produce low mood on their own, and separating that from a drug effect is genuinely hard.
Happy to go further on any of that.
amsterdam_pete said:The weight came off and the harder part started, which is not what any of the material I read had prepared me for.
When to call your doctor about mental health side effects — a reference I wish I'd had:
Call immediately:
- Severe abdominal pain (could be pancreatitis)
- Vision changes (thyroid concern)
- Lump in neck (thyroid nodule)
- Severe vomiting/can't keep fluids down for 24h+
Schedule an appointment:
- Persistent nausea beyond 4 weeks
- Significant hair loss
- Mood changes or depression
- Gallbladder symptoms (RUQ pain after eating)
Dr.LipidDallas said:I would be careful about how confidently the flatness reports get attributed.
Anxiety increase on mental health: counterintuitive, but losing weight rapidly triggered anxiety for me. Change — even positive change — is stressful. I was anxious about whether I deserved to feel good.
This is more common than people admit. A therapist who specializes in weight management has been invaluable. Don't neglect the mental health side of this journey.
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Browse GL BiochemA narrower follow-up, since the general answer is now clear:
What did you change at the same time, and can you separate the two now?
Reporting back.
Update: I got the sleep and the intake sorted before deciding it was the drug, and most of the flatness went with them. Not all of it, and I am watching the rest.