I am tired in a way that does not respond to sleep, which is different from the tiredness I had before any of this started.
Worth checking before concluding it is the drug: ferritin, B12, TSH, and total intake for three honest days. Two of those four explain most cases.
The narrow version of the question is whether the fatigue is a direct drug effect or simply the caloric deficit, because the answer changes what you do about it.
If the honest answer is that nobody knows, that is a useful answer and I would rather have it.
Taking the question as asked, rather than the general version of it. Take it one variable at a time. Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent argument can untangle them after the fact.
If somebody has the primary source to hand I would rather cite it than paraphrase it.
LarryQC_SD said:Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent…
Agreed, and the size of the effect matters as much as its existence. Something real and small gets treated here as though it were real and decisive.
Janoshik Analytical — Independent Testing
Trusted third-party HPLC & mass spectrometry analysis. Verify peptide purity with the lab the community relies on. Independent. Accurate. Transparent.
Verify Your PeptidesGL Biochem (Shanghai) Ltd. — Direct Manufacturer
Est. 1998. The synthesis house behind the vials you send for testing. ISO 9001 and cGMP certified, 1,500+ staff, batch-specific COA with every order.
Browse GL BiochemSleepFixSam said:I am tired in a way that does not respond to sleep, which is different from the tiredness I had before any of this started.
Same pattern here, and in the same order.
Clinical perspective, offered as context rather than as advice. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.